Vitamin B12 is primarily sourced from meat, making deficiencies more common among: Vegans and vegetarians Busy and active mums Individuals recovering from surgery Those on weight loss journeys Regular injections throughout the year or a structured course of treatment can help restore and maintain your vitamin levels
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B12 is a key player in the production of the mood-regulating chemical serotonin and when your body is lacking the vitamin, production can decrease
5-Amino-1MQ: primarily rodent studies, no published human trials
According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment
Its clinical development was halted after Phase 2b trials