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To prevent ROS production from semiquinones, the cytosolic, NRF2-regulated flavoproteins NAD(P)H: quinone oxidoreductases (NQOs) and aldo-keto reductase (AKR) can compete with P450 reductases and convert quinones to a relatively stable hydroquinones (quinols) [35]
Trends Pharmacol Sci 27:639645 Chance B, Hollunger G (1961) The interaction of energy and electron transfer reactions in mitochondria
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Patients with IBS, IBD, or post-antibiotic gut dysregulation frequently use BPC-157 orally or sublingually, where it acts locally on the gut mucosa
Factors associated with progression of Barretts esophagus: a systematic review and meta-analysis
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