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Well be watching for liver effects very carefully, Ryan said
We also announced the addition of an extra MAD cohort to the ongoing Phase I GLP-131 study evaluating BMF-650, our investigational oral GLP-1 receptor agonist, to explore a rapid one-step titration potential and to further optimize its weight reduction potential
They can be detected through specialized testing
These changes were accompanied by reductions in pro-inflammatory cytokines such as IL-6 and TNF- and increases in the anti-inflammatory cytokine IL-10 [5]
N Engl J Med 2021
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