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The increased numbers of CD21 low B cells implicated in autoimmunity (164167) were also reported in Kabuki syndrome type 1, Rubinstein-Taybi syndromes type 1 and type 2 ( Figure 6G ) (60, 77, 83, 115, 126128) which in some cases were accompanied by autoimmune diseases (83, 115, 126128)

Testicular blood flow was evaluated through scanning of the supra-testicular artery (STA) spectral patterns through pulsed Doppler ultrasonography [peak systolic velocity (PSV), end-diastolic velocity (EDV), time average maximum velocity (TAMAX), resistive index (RI), and pulsatility index (PI)], while the echotexture assessment of testicular parenchyma was performed by a computerized software program

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It is used in addition to a low-calorie diet and physical activity

Microscopic examination of mouse colonic tissue reveals reduced inflammatory cell infiltration, maintained crypt morphology, and fewer surface defects in the PYY group compared to controls (Supplementary Fig