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Researchers designing combination protocols should treat the combination as an area of active investigation with mechanistic rationale rather than an established protocol with defined clinical outcomes

The revised CLASI includes adjustments to the original CLASI, such as new variables like edema/infiltration and subcutaneous nodules/plaques

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Imaging with transvaginal ultrasound, saline sonohysterography, or MRI helps find these issues

Standard reconstitution produces injectable solution

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