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The 8mg dose achieved 21.1% weight loss (matching Zepbounds efficacy) with lower side effects: 24% nausea versus 28% at 12mg, 8.4% discontinuation versus 11.2%

For some patients, staying on a GLP long term is the healthiest option, just like being on a statin or blood pressure medication

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If you continue experiencing ED for several weeks, this could indicate long-term side effects associated with semaglutide

Phosphodiesterase 4b: master regulator of brain signaling

The association between GLP-1 receptor agonist and diabetic ketoacidosis in the FDA adverse event reporting system