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This area is commonly used when a larger volume of medication needs to be injected

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10.1007/s12010-024-05003-4 105 LiN.LuX.YangY.NingS.TianY.ZhouM.et al (2024)

KPV's anti-inflammatory contribution is relevant here: synovial inflammation is a consistent feature of chronic joint stress models, and the reduction of IL-1 and TNF- that KPV demonstrates in cell culture models would be a logical correlate in a joint-stress research context [7]

The trade-off: Injections deliver the molecule most efficiently, but they dramatically raise the "risk floor" due to issues like sterility and systemic allergic responses

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