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After 4-hour incubation, reductive GSH levels were detected using a GSH test kit (Beijing Solarbio)

In addition, it did not provoke non-specific toxicity in normal cells and organs, confirming its safety for AML therapy

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6 Conclusion and perspective Iron, an essential trace element and pivotal signaling molecule in the nervous system, can drive ferroptosis, which contributes to the pathogenesis of NDDs such as AD, PD, MS, and ALS