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A 2025 HSS Journal systematic review (544 articles screened, 36 included 35 preclinical, 1 clinical) concluded that high-quality clinical evidence remains limited and use should be approached with caution
If side effects become unbearable, your PlexusDx provider can hold your current dose, reduce it temporarily, or explore alternative compounds like compounded tirzepatide or the microdose GLP-1 protocol
HSS Journal: The Musculoskeletal Journal of Hospital for Special Surgery , 21(3), 115
Clinical Nutrition Open Science, 41, 100065
The active compounds are ginsenosides, which work through multiple mechanisms: enhanced nitric oxide production, support for the brain signaling behind focus and memory, and modulation of the HPA axis stress response
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