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The FAO activity assay is based on the oxidation of octanoyl-CoA, which is coupled to NADH-dependent reduction of INT to INT-formazan, and exhibits an absorption maximum at 492 nm [59]
A deficiency of acid phosphatase activity in the lysosomal fraction, presumably due to impairment of the ACP2 protein, manifests as intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding and death in early infancy (136)
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Archives of toxicology
Moreover, Thy-rich Nigella sativa seed oil exerts an antioxidant effect as an adjuvant therapy in hypertensive patients, mainly manifested in the upregulation of serum glutathione reductase (GR) levels and reduction of serum MAD content