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Larbig et al
MAPK/ERK Cascade and GILZ Homology Computational and molecular research identified structural homology between DSIP and GILZ (glucocorticoid-induced leucine zipper) a glucocorticoid-regulated protein that prevents Raf-1 activation and thereby inhibits ERK phosphorylation via the MAPK cascade
Whilst manufacturers claim superior bioavailability compared to standard forms, independent clinical evidence supporting these claims in the context of liver disease remains limited
This is the mechanistic basis for the compound's metabolic effects
Antioxid (Basel) 11(6)
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