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More physiologically relevant models such as 3D organoids, patient-derived xenografts, and genetically engineered mice are needed to better predict nanoplatform behavior

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To mitigate the risk of elevated TMAO while maximizing the therapeutic benefits of carnitine, clinical guidelines suggest adhering to moderate, divided doses rather than single massive boluses

Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats

Yue T, Shi Y, Luo S, Weng J, Wu Y, Zheng X

Long-term cost-effectiveness of subcutaneous once-weekly semaglutide versus polyethylene glycol loxenatide for treatment of type 2 diabetes mellitus in China