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Dihexa is studied for its proposed capacity to function as a potentiator of hepatocyte growth factor (HGF) at the MET receptor tyrosine kinase, rather than acting as a direct receptor agonist
Overall, when administering GLP-1RA plus SGLT2i combination therapy, it is important to adopt an individualized approach to therapy taking into account individual preferences, costs and coverage, AE profile, consideration of kidney function and glucose-lowering efficacy, desire for weight loss, and comorbidities such as frailty [6, 22, 24]
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Weekly pills and monthly injections are all in development