Discontinuation due to factors typically irrelevant in clinical trial settings (i.e., cost or insurance-related issues and medication shortages) could contribute to the substantial discrepancy between discontinuation rates in pivotal phase 3 trials and those reported in real-world studies. Regarding discontinuation due to side effects, Gasoyan says we do not currently know of patient-level predictors that would help identify who might experience side effects and why
Managing Side Effects While Taking Rybelsus Effective management of side effects can significantly improve treatment adherence and outcomes with Rybelsus
We also provide ongoing monitoring of your B12 levels to ensure your treatment is effective and adjusted as needed
Lin SH, Myles BH, Wang L, Thall PF, Vaporciyan AA, Mehran RJ, Swisher S , Lee JH, Bhutani MS, Maru D, Ajani JA, Cox JD, Komaki R, Liao ZX
Patients with pancreatic cancer have higher levels of serum fructose which induces TKT expression to drive nucleic acid synthesis in cancer cells (104)
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