Long-Term Perspective: Obesity is a chronic, relapsing condition
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Bailey Bryan, Updated 2/17/2026 Shelly House, FNP, is a Family Nurse Practitioner and Call-On-Docs trusted medical education voice
Moreover, it appears that it is the membrane-bound form of the enzyme, on sites such as the luminal surface of capillary endothelial cells, which is more important for GLP-1 degradation than the circulating (soluble) enzyme (74, 75), questioning the relevance of any association between the plasma activity per se and glycaemic control, since it is unclear whether changes in soluble DPP-4 activity in the circulation accurately reflect any changes in total DPP-4 activity
"They've just had it prescribed for weight loss purposes actually one of them was taking it to help lower their blood sugar, but they literally wanted to take it to lose weight." Mr Curtis competes in "natural" bodybuilding competitions, meaning he is subject to drug testing