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The next decade may redefine how we approach metabolic and chronic diseases #GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety

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Jun 2011;3(2):69-75

RNA sequencing (RNA-seq) analysis Total RNA from fibroblasts was extracted using TRIzol (Takara Bio, Tokyo, Japan)

The new indication could give Novo Nordisk a boost against rivals in the GLP-1 agonist class, including Eli Lilly, whose dual GIP/GLP-1 agonist Mounjaro (tirzepatide) competes in the diabetes category and is in a phase 3 trial (TREASURE-CKD) looking at a CKD indication in people with obesity, with and without diabetes