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Cell Metabolism 2022 02 Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial Jastreboff AM, Kaplan LM, Fras JP, et al

Injectable peptide therapies rely on highly specialized capabilitiesincluding injection molding, pen assembly, recombinant fermentation or solid-phase peptide synthesis, sterile fill-finish and cold-chain logisticsall requiring dedicated facilities, technical expertise and years of investment

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The peptide also increases growth hormone receptor expression on fibroblasts, the cells responsible for producing collagen and other structural proteins

McMinn, J