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Other combination tablets may pair metformin with a different medicine class
Metformin was discovered to be taken up by transporter proteins on the apical membrane surface of small intestinal epithelial cells in a study conducted on Caco-2 cells
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The intestinal absorption of carnitine, as well as its renal reabsorption, is primarily mediated by the plasma membrane organic cation transporter novel 2 (OCTN2 SLC22A5) that, among the carnitine-handling transporters, shows the highest affinity toward carnitine
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