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In this 72-week study of 2,539 adults [1] with obesity, participants receiving 15mg weekly tirzepatide achieved an average weight reduction of 22.5% compared to 2.4% with placebo

Both medications also improved key health markers such as blood glucose and blood pressure

Insulin has stimulatory effects on ovarian androgen production 5,11 , and enhances the bioavailability of testosterone by decreasing the hepatic release of sex hormone-binding globulin (SHBG) 12

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Additionally, these liposomes act as permeation enhancers by interacting with and disrupting the organized lipid matrix of the SC, particularly by altering the structure of the intracellular lipid lamellae