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Metabolic implications beyond glucose control Beyond glucose control, GLP-1RAs may affect liver triglyceride levels, fat metabolism, and the conversion of white adipose tissue into brown adipose tissue, as shown in animal studies

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For example your face may appear hollow around the cheeks or eyes, or you might have significant loose skin around the abdomen or other areas of the body

Miller R, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock : Methionine deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels and increases hepatocyte MIF levels and stress resistence

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