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Using pharmacy receipt data anchored to initial GLP-1 prescriptions in 2021 from a large PBM, one early study revealed that only 32% GLP-1 patients remained on these weekly injections after 12 months and only 15% after two years.[16] This is an 85% two-year rejection rate not too far off from otherwise successful, consumer packaged goods brands Ive worked with

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What happens if you stop taking GLP-1s

N Engl J Med 355:22972307 Aithal GP, Thomas JA, Kaye PV et al (2008) Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis

Mol Metab 2020;34:16-26.ArticlePubMedPMC 72