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SKU: 49426097227
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Description

Metformin, the only biguanide medication currently available for the treatment of diabetes, is considered the first-line drug for type 2 diabetes (Misbin 2004

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The parasite genome demonstrates significant instability characterized by aneuploidy, copy number variations (CNVs), and single nucleotide polymorphisms that collectively facilitate rapid adaptation to therapeutic interventions ( Leishmania to develop resistance through various mechanisms including altered drug transport, target modification, and enhanced metabolic detoxification pathways ( Leishmania serves as an evolutionary advantage, allowing rapid selection of resistant populations under drug pressure

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