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Vitamin B12 insufficiency that is not due to poor dietary intake is often treated with hydroxocobalamin injections once every 2-3 months for the rest of one's life

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A meta-analysis of 15 randomized controlled trials showed modest BMI reduction with inositol supplementation, with the strongest evidence in PCOS populations where inositol improved insulin resistance and showed non-inferiority to metformin in 26 RCTs involving 1,691 patients