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summary Some animal studies suggest that a deficiency in vitamin B12 may increase body fat percentage and alter metabolism

Published investigations differ according to: Experimental model Laboratory methodology Product concentration Research duration Biological endpoints Scientific objectives Researchers also recognize the importance of maintaining standardized laboratory practices throughout every investigation

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Finally, a doctor tested for Intrinsic Factor Anti-body, which prevents B12 absorption

Some patients find that taking their supplement with the largest meal of the day provides optimal tolerance