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While no clinical trials have examined BPC-157 for hip conditions directly, extensive preclinical work on tendons, ligaments, and muscles provides strong mechanistic support for its application to hip problems

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This graduated escalation reduces the likelihood of side effects and gives the clinician time to assess patient response at each tier

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In humans, PAGln enhances platelet reactivity and thrombotic potential through ADR signaling, accelerating thrombus formation in arterial injury models while promoting systemic inflammation and endothelial dysfunction to drive atherosclerosis (Fang et al., 2022)