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However, topline results released by NovoNordisk stated that their two phase 3 trials investigating once-daily oral semaglutide in early-stage Alzheimers disease (clinical trial numbers NCT04777396 and NCT04777409) did not confirm the superiority of semaglutide versus placebo in reducing the progression of Alzheimers disease, as measured by the change in Clinical Dementia Rating Sum of Boxes score compared with baseline

However, the absolute increase was in the low physiological rangetypically 2030% above baselinecompared to the 5- to 10-fold increases seen with compounded semaglutide injections

Symptomatic management remains important throughout the course of the disease and consists of everyday practical measures to deal with the primary symptoms of joint stiffness, such as pain and fatigue

It's a powerful tool for patients who may need a different approach than Semaglutide

For the complete breakdown of all trials, see our clinical results guide

I used it approximately 20 days