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Hypertension, Angiotensin II, and Oxidative Stress

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Biochemical Pharmacology (2018) 2

[33] [34] However, too low and excessively high levels of choline may adversely affect fetal health and development

When used together, there may be an additive effect on heart rate , which could be clinically significant in patients with pre-existing cardiovascular conditions, including hypertension, arrhythmias, or coronary artery disease