In the presence of high concentration of H 2 O 2 in tumor microenvironment, the bisboronate group is cleaved, resulting in activation of 5-DFUR for chemotherapy and activation of NPS for NIR photodynamic therapy
Patients in occupations where avoidance is difficult may experience work-related stress, in addition to the existing stigmas those with visible hand lesions may face social stigma, further diminishing QoL [55]
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For many patients, GLP 1 medications are one part of a broader care plan that may also include nutrition, movement, behavioral support, and ongoing clinical monitoring