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Why is vitamin B12 important for pregnancy and postpartum
the four mechanisms behind it (neuroinflammation, fuel, hormones and BDNF plasticity), with the 2024 Nature Neuroscience bloodbrain-barrier evidence and the Gladstone fibrin research
These hormones are helpful during short-term stress, but in long-term stress they cause nothing but problems
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Unlike most vitamins, B12 has a uniquely complex absorption pathway: Stomach acid and pepsin release B12 from food proteins B12 binds to R-proteins (haptocorrins) in saliva and stomach Pancreatic enzymes release B12 from R-proteins in the small intestine B12 binds to intrinsic factor (produced by gastric parietal cells) The B12-intrinsic factor complex is absorbed in the terminal ileum A breakdown at any of these five steps causes deficiency which is why B12 deficiency is far more common than dietary intake alone would predict
B12s role in maintaining healthy circadian rhythms may help prevent the sleep disturbances and daytime fatigue commonly experienced with SAD
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