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While recent incretin-based therapies have provided pharmaceutical inroads into treatment of obesity, there remains an ongoing need for additional medicines with distinct modes of action as independent or complementary therapeutics

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The Multiomics View: What Makes It Clinically Interesting Where things click for me is in the systems biology lens

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Side Effects and Tolerability The dominant side effects of both amylin analogs and incretin agonists are gastrointestinal : nausea, vomiting, diarrhea, and constipation