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Individual dosing should be personalized based on body weight, baseline body composition, metabolic status, response to therapy, and physician assessment

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Nature 2023;619:143150

It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported

If you're leaning towards mornings, you might find useful keeping your vitamin B12 supplements right next to your bed or in your bathroom's medicine cabinet, so that you can get a daily visual cue that will make taking vitamin supplements in the morning as easy as remembering to brush your teeth