These data suggest that a mGIPR-Ab/GLP-1 peptideantibody conjugate may act on a different population of cells or via distinct molecular mechanism(s) compared to GIPR agonists like tirzepatide
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For the first time, clinicians have pharmacologic tools that produce durable, clinically meaningful weight loss in a field where most older options were modest, short-lived, or poorly tolerated
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This dual agonist design is what makes tirzepatide different from semaglutide and other GLP-1 only agonists