A study of postmenopausal women with overweight or obesity, published in the Lancet Obstetrics, Gynaecology, & Womens Health in early 2026, found that women taking tirzepatide plus hormone replacement therapy lost more weight than women taking tirzepatide alone
Claims that a capsule recreates natural GLP-1 pharmacology should be treated skeptically unless supported by rigorous human data and transparent dosing
Deficiencies in B vitamins or imbalances in SAH and SAM increase GSH breakdown by GGT, releasing hydrogen sulfide (H2S)
Vitamin B12, vitamin D, and ferritin (your iron stores) can all drift down when intake falls, and deficiencies in these show up as fatigue long before anything dramatic
Seizures: An increase in seizure frequency or severity has been reported in people with a history of seizures who have used L-carnitine orally or intravenously
As the use of GLP-1 drugs like Ozempic, Wegovy, Mounjaro, and Zepbound continues to skyrocket, there are also increasing concerns about hair loss among users of Ozempic and other GLP-1s
