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In addition, blockade of sodium channels, high-voltage calcium currents, carbonic anhydrase isoenzymes, and mitochondrial permeability transition pore (MPTP) may also contribute to its neuroprotective effects
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The effect of Gem pretreatment on ferroptosis in HT-1080 cells was reversed by co-treatment with BSO, consistent with a GSH-dependent mechanism (Fig 4E)
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