Koutsakos M, Illing PT, Nguyen T, Mifsud NA, Crawford JC, Rizzetto S, et al
Side effects are rare and typically mild, such as temporary irritation or redness at the injection site
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Store lyophilized peptide between 20C and 80C
After a single hydroxocobalamin injection, therapeutic levels can be maintained for approximately 8 to 12 weeks in most patients, which aligns with the standard maintenance schedule of injections every 2-3 months recommended in the British National Formulary (BNF)
Engineering a Stabilized Analogue at Metabolic Pharmaceuticals (mid-1990s2000) The native 177 to 191 fragment was a useful demonstration but not, in its raw form, a candidate for oral drug development