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The mechanism is not fully established, but the preservative may offer a mild stabilizing effect on certain peptide bonds
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Apparently, metformin acts directly on gut bacteria to increase their vitamin B12 uptake, leading to increasing competition for available dietary vitamin B12 and ultimately to human vitamin B12 deficiency (55)
The general principle is straightforward
[114] This functionality is lost in vitamin B 12 deficiency, and can be measured clinically as an increased serum methylmalonic acid (MMA) concentration
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