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Concurrently, SIRT1 activates AMPK and inhibits the mTOR pathway, releasing inhibition of autophagy and increasing clearance of lipid droplets and damaged mitochondria

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McCarley, R

Zarai Z, Boujelbene E, Ben Salem N, Gargouri Y, Sayari A

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For instance, transmission electron microscopy (TEM) and PLAs reveal that the abundance of ER-mitochondria contacts is increased in effector memory CD8+ T cells (CD62L CD45RA populations)