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Nishimura M, Tokoro T, Takatani T et al (2015) Effects of intravenous l-carnitine on myocardial fatty acid imaging in hemodialysis patients: responders or non-responders to l-carnitine

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Average responders see 5 to 10%

For example, someone living with a congenitally small canal can develop mild to moderate arthritis or a disc herniation that otherwise might not be large enough to be symptomatic