A: Yes, clinical trials have found that semaglutide (the GLP-1 in the generic medications in Canada) significantly increases a biological marker of bone resorption, indicating bones are being broken down and that there is significantly lower Bone Mineral Density (BMD) at the lumbar spine, total hip, and tibia, which escalates the long-term risk for osteoporosis and fractures
Kablinger, Carilion Clinic, director of clinical research, Department of Psychiatry and Behavioral Medicine, Virginia Tech Carilion School of Medicine The late Warren K
Importantly, these consequences of virus-mediated proteolysis would be taking place in everyone who is actively infected, regardless of their Se status , and would thus be consistent with results suggesting that Se intakes up to several times the minimal dietary requirement are associated with an increase in cure rate from COVID-19 (1)
Direct answer: Semaglutide is generally safe long-term, but patients should expect ongoing digestive effects and require routine monitoring
For instance, increasing protein intake has been shown to reduce hunger and improve satiety, which may aid in overcoming weight loss stalls
This can be especially beneficial if youre experiencing stress-related cognitive issues
