Although meta-analysis (97 comparisons across 95 trials) demonstrated a statistically significant but clinically unimportant increase in FPG [fasting plasma glucose] (Hall et al., 2020), the impact of any diuretic on glucose homeostasis seems to depend on several factors, including the type of diuretic used and the specific metabolic context on which these diuretics are being studied (Grossman et al., 2011)
arXiv preprint arXiv:1810.04805
Handling and Storage of Frusemide/Spironolactone Recommended Storage Conditions The medication should be stored at room temperature, away from direct sunlight and moisture, to maintain its pharmacological efficacy
Maximum efficacy is generally achieved at doses of 10-15 mg weekly
If they dont, a clinician can help rule out other contributors
If you experience noticeable hair loss, bring it up with your doctor.