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A lack of noticeable change in the first week does not provide useful evidence about long-term effectiveness

The skin may be thinner, the distribution of the residual fat may be less predictable, and areas of fibrous tissue from prior fat deposits may need particular procedures to be treated well

Patience helps

Patients using semaglutide are typically asked to reduce their intake by about 500 calories a day and get at least 150 minutes of exercise per week

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Contrave: Common side effects may include nausea, constipation, headache, vomiting, dizziness, insomnia, and increased blood pressure