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The initial attempts to induce DE differentiation using small-molecule cocktails containing CHIR and IDE1 (CI-I and CI) proved inefficient
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Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomized, double-blind, placebo-controlled, phase 3 trial
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They then increased the EAR by 20% to arrive at an RDA of 2.4 g which aims to cover the needs of 97% to 98% of the population
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