Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]
For anyone tracking the broader category of medications that target liver fat, understanding how mazdutide compares to retatrutide provides additional context on the competitive landscape
The Lancet Diabetes & Endocrinology , June 21, 2025 Copyright 2025 HealthDay
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