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The medication enhances insulin secretion and inhibits glucagon release, which helps in maintaining stable blood glucose levels

This indicates that its proliferative and cytoprotective effects on the gut epithelium are mediated indirectly via paracrine signaling (6467)

The rate of weight regain was not influenced by intensity of behavioural support during drug treatment, nor by behavioural support or metformin compared to no support after drug cessation

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GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism

Request hsCRP at baseline if not included in standard bloodwork