Sitohang IBS, Makes WI, Sandora N, Suryanegara J
As sought-after as skin lightening is, some of the chemicals used for it are highly toxic
Kramerova, I., Kawaguchi, N., Fessler, L., Nelson, R, Chen, Y., Kramerov, A., Kusche-Gullberg, M., Kramer, J.M, Ackley, B., Prockop, D., Fessler, J.H, "Papilin in development: a pericellular protein with a homology to the ADAMTS metalloproteinases", Development 127: 5475-5485 (2000)
It was never approved
Molecular oxygen (O 2 ) can unpair and leave free radicals which are highly unstable and reactive, leading to the formation of ROS [45, 46]