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Daniell K, Nucera C
Semaglutide, the active ingredient in Ozempic, works through two distinct pathways: it slows stomach emptying within the first dose, and it signals your brain's appetite centers over weeks of treatment
Diabetes Ther 16 , 12071227 (2025)
Most side effects improve substantially within 4-8 weeks of starting treatment or after each dose increase, and many patients find that the benefits of improved glycemic control and weight loss outweigh the temporary discomfort of initial side effects
However, some current theories are shown in Fig
For example, if semaglutide is not absorbed or used by the body as effectively, it might not control blood sugar as well, leading to higher blood sugar levels in people with diabetes
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