Hematological testing also revealed no significant toxic effects on red blood cells, white blood cells, or platelet counts (Figs
S., SriRamaratnam, R., Welsch, M
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Although cytosolic CPS2 can produce a cytosolic pool of carbamoyl phosphate, CPS1 is a major rate-limiting enzyme in pyrimidine biosynthesis using nitrogen released via mitochondrial glutaminolysis 32
If a meal feels too large, eat the protein first and save the rest
But skin reactions are common: contact dermatitis, adhesive irritation, redness, and occasional blistering