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This gradual dose escalation helps minimize gastrointestinal adverse effects

Plus, certain individuals, such as those who are overweight or have pre-existing gastrointestinal disorders, may be at a higher risk of developing stomach pain as a side effect of taking semaglutide

GLP-1 treatment can also positively impact people with poor control of their blood sugar, blood pressure, and/or cholesterol levels, contributing to improved long-term health outcomes

Research has demonstrated that simultaneous GIP and GLP-1 receptor stimulation creates a synergistic insulin response and glucagonostatic effect significantly greater than what separate administration of each hormone produces

For veterans with pre-existing type 2 diabetes, dose adjustments of sulfonylureas or insulin may be necessary to avoid hypoglycemia

The mental health dimension of side effects deserves attention too