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These peptides mimic the spatial conformation of the parent (native) molecules while exhibiting significantly enhanced resistance to enzymatic degradation, thereby enabling prolonged biological activity and reduced immunogenicity
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Thus, we can assume that pathways additional to those involved in angiogenesis (Vukojevic et al., 2018) are associated with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)
Infection with HSV-2 can cause genital ulcerations, which may be accompanied by fever, local lymphadenopathy and dysuria, and infected individuals have a lifelong risk of transmitting the viral infection to their sexual partners
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