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Phase 2 trial data (published in the New England Journal of Medicine, 2023) have demonstrated significant weight loss and improvements in glycaemic markers, but the complete safety profile including the precise risk of low blood sugar continues to be characterised

Because of its dual benefits for blood sugar control and weight loss, semaglutide is sometimes considered by people preparing for IVF, particularly if they need to lose weight to improve their chances of success

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Other protocols potentially of interest include Cancer Radiation Therapy, Cancer Surgery, Cancer Adjuvant Therapy, and Cancer Immunotherapy

Retatrutide is the more potent option for those willing to accept the additional unknowns in exchange for potentially superior body composition results

In one study, more than half of patients maintained weight loss achieved while on semaglutide or liraglutide one year after discontinuing the medication